MUC-1 Monoclonal / CF680R / HMPV

Product Details
Supplier Biotium
Catalog #: BNC810954-100 (View supplier product page)
Size 100 μl
Price $157.00
Antigen MUC-1
Clone HMPV
Host Mouse
Isotype IgG1 κ
Conjugate CF680R
Target Species Human
Applications IF, IHC-P, FC
Description Mucin 1 / EMA / Episialin / CD227 Monoclonal Mouse Antibody (HMPV)
About MUC-1 and CF680R
MUC-1 This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
CF680R CF®680R from Biotium is a fluorophore with an excitation peak at 680 nm and an emission peak at 701 nm. It can be useful in both fluorescence microscopy and flow cytometry. For microscopy, CF®680R has been specifically validated in super-resolution imaging by STORM, STED and 2-Photon microscopy. It is spectrally similar to Alexa Fluor™ 680, IRDye® 680 and Cy5.5.
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CF680R Excitation and Emission Spectra