MUC-1 Monoclonal / CF555 / MUC1/967

Product Details
Supplier Biotium
Catalog #: BNC550967-500 (View supplier product page)
Size 500 μl
Price $470.00
Antigen MUC-1
Clone MUC1/967
Host Mouse
Isotype IgG1 κ
Conjugate CF555
Target Species Human
Applications IF, IHC-P, FC
Description Mucin 1 / EMA / Episialin / CD227 Monoclonal Mouse Antibody (MUC1/967)
About MUC-1 and CF555
MUC-1 This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
CF555 CF®555 from Biotium is a fluorophore with an excitation peak at 555 nm and an emission peak at 565 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 555, ATTO 550 and DyLight™ 550. In Flow Cytometry, R-PE is a brighter alternative to CF®555. In microscopy, it has been validated for use in super-resolution imaging by STORM.
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CF555 Excitation and Emission Spectra