CD305 Monoclonal / CF405S / 9.1C3

Product Details
Supplier Biotium
Catalog #: BNC040973-100 (View supplier product page)
Size 100 μl
Price $120.00
Antigen CD305
Clone 9.1C3
Host Mouse
Isotype IgG2 κ
Conjugate CF405S
Target Species Human
Applications IF, FC, Block/Neutralize
Description Mouse Monoclonal anti-LAIR-1 / CD305 (9.1C3)
About CD305 and CF405S
CD305 The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
CF405S CF®405S from Biotium is a fluorophore with an excitation peak at 404 nm and an emission peak at 431 nm. It is spectrally similar to Alexa Fluor™ 405. It can be use in fluorescence microscopy, specifically its been validated in Structured Illumination (SIM), and flow cytometry. However, in flow cytometry, superior alternatives are Brilliant™ Violet 421, SuperNova v428 and StarBright Violet 440.
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CF405S Excitation and Emission Spectra