FluoroFinder

	Supplier	Biotium
	Catalog #:	BNC471421-100 (View supplier product page)
	Size	100 μl
	Price	$199.00
	Antigen	Clathrin Light Chain
	Clone	CLC/1421
	Host	Mouse
	Isotype	IgG2b κ
	Conjugate	CF647
	Target Species	Human
	Applications	IHC, IHC-P
	Description	This antibody recognizes proteins of 31-44 kDa, which are identified as Clathrin Light Chains (both A & B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

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$199.00
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Clathrin Light Chain Monoclonal / CF647 / CLC/1421