CD8a Monoclonal / CF543 / C8/468 + C8/144B

Product Details
Supplier Biotium
Catalog #: BNC430750-100 (View supplier product page)
Size 100 μl
Price $157.00
Antigen CD8a
Clone C8/468 + C8/144B
Host Mouse
Isotype IgG
Conjugate CF543
Target Species Human
Applications IF, IHC-P, FC
Description CD8 Monoclonal Mouse Antibody (C8/468 + C8/144B)
About CD8a and CF543
CD8a The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
CF543 CF®543 from Biotium is a fluorophore with an excitation peak at 541 nm and an emission peak at 560 nm. It can be useful in both fluorescence microscopy and flow cytometry.
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CF543 Excitation and Emission Spectra