CD38 Monoclonal / CF405M / AT1

Product Details
Supplier Biotium
Catalog #: BNC050430-500 (View supplier product page)
Size 500 μl
Price $470.00
Antigen CD38
Clone AT1
Host Mouse
Isotype IgG1 κ
Conjugate CF405M
Target Species Human
Applications IF, FC
Description CD38 Monoclonal Mouse Antibody (AT1)
About CD38 and CF405M
CD38 The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
CF405M CF®405M from Biotium is a fluorophore with an excitation peak at 408 nm and an emission peak at 452 nm. It is spectrally similar to Pacific Blue, V450 and DY-415. It can be use in fluorescence microscopy and flow cytometry. Specifically, it has been validated for use in STED, Structured Illumination (SIM) and 2-Photon microscopy. In flow cytometry, superior alternatives are Brilliant™ Violet 480, Brilliant™ Violet 510 and StarBright Violet 515.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

CF405M Excitation and Emission Spectra