CD27 Monoclonal / CF543 / LPFS2/1611

Product Details
Supplier Biotium
Catalog #: BNC431611-500 (View supplier product page)
Size 500 μl
Price $470.00
Antigen CD27
Clone LPFS2/1611
Host Mouse
Isotype IgG1
Conjugate CF543
Target Species Human
Applications IF, IHC-P, FC
Description CD27 Monoclonal Mouse Antibody (LPFS2/1611)
About CD27 and CF543
CD27 The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
CF543 CF®543 from Biotium is a fluorophore with an excitation peak at 541 nm and an emission peak at 560 nm. It can be useful in both fluorescence microscopy and flow cytometry.
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CF543 Excitation and Emission Spectra