Bcl-10 Monoclonal / CF660R / BL10/411

Product Details
Supplier Biotium
Catalog #: BNC610411-100 (View supplier product page)
Size 100 μl
Price $157.00
Antigen Bcl-10
Clone BL10/411
Host Mouse
Isotype IgG1 κ
Conjugate CF660R
Target Species Human
Applications IF, IHC-P, FC, WB
Description BCL-10 Monoclonal Mouse Antibody (BL10/411)
About Bcl-10 and CF660R
Bcl-10 This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
CF660R CF®660R from Biotium is a fluorophore with an excitation peak at 662 nm and an emission peak at 682 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 660.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

CF660R Excitation and Emission Spectra