VEGF 165 Monoclonal / CF568 / VEGF/1063

Product Details
Supplier Biotium
Catalog #: BNC681063-500 (View supplier product page)
Size 500 μl
Price $551.00
Antigen VEGF 165
Clone VEGF/1063
Host Mouse
Isotype IgG1 κ
Conjugate CF568
Target Species Canine, Human, Mouse, Rabbit, Rat
Applications IHC, IHC-P
Description This MAb recognizes proteins of 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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CF568 Excitation and Emission Spectra