S100B Monoclonal / CF543 / 4C4.9 S100B/1012

Product Details
Supplier Biotium
Catalog #: BNC431204-100 (View supplier product page)
Size 100 μl
Price $157.00
Antigen S100B
Clone 4C4.9 S100B/1012
Host Mouse
Isotype IgG2a κ
Conjugate CF543
Target Species Bovine, Human, Mouse, Rat
Applications IF, IHC-P, FC, WB
Description S100B Monoclonal Mouse Antibody (4C4.9 + S100B/1012)
About S100B and CF543
S100B The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]
CF543 CF®543 from Biotium is a fluorophore with an excitation peak at 541 nm and an emission peak at 560 nm. It can be useful in both fluorescence microscopy and flow cytometry.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

CF543 Excitation and Emission Spectra