p53 Monoclonal / CF543 / BP53-12 DO-7
p53 Monoclonal / CF543 / BP53-12 DO-7
Product Details
| Supplier | Biotium | |
|---|---|---|
| Catalog #: | BNC430723-100 (View supplier product page) | |
| Size | 100 μl | |
| Price | $157.00 | |
| Antigen | p53 | |
| Clone | BP53-12 DO-7 | |
| Host | Mouse | |
| Isotype | IgG | |
| Conjugate | CF543 | |
| Target Species | Bovine, Human, Monkey | |
| Applications | IF, IHC-P, FC, WB | |
| Description | p53 Tumor Suppressor Monoclonal Mouse Antibody (Bp53 Tumor Suppressor-12 + DO-7) |
About p53 and CF543
| p53 | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] | |
|---|---|---|
| CF543 | CF®543 from Biotium is a fluorophore with an excitation peak at 541 nm and an emission peak at 560 nm. It can be useful in both fluorescence microscopy and flow cytometry. |
Citations
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Reviews & Ratings
CF543 Excitation and Emission Spectra
$157.00
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