FluoroFinder

	Supplier	Biotium
	Catalog #:	BNC470673-500 (View supplier product page)
	Size	500 μl
	Price	$551.00
	Antigen	Cyclin A2
	Clone	E67
	Host	Mouse
	Isotype	IgG2a κ
	Conjugate	CF647
	Target Species	African Green Monkey, Bovine, Human, Mink, Monkey, Mouse
	Applications	IHC, IHC-P, WB
	Description	This antibody recognizes a protein of 54 kDa, which is identified as cyclin A. Its epitope is located in amino acids 144-148 of human Cyclin A2. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk's) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdk's. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while cyclin B is a critical regulator of mitosis. Mutation or disruption of normal cyclin A expression causes cells to arrest in G2-phase. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

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$551.00
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Cyclin A2 Monoclonal / CF647 / E67