Neurofilament Heavy 200kDa Monoclonal / CF770 / NF421

Product Details
Supplier Biotium
Catalog #: BNC700421-100 (View supplier product page)
Size 100 μl
Price $157.00
Antigen Neurofilament Heavy 200kDa
Clone NF421
Host Mouse
Isotype IgG1
Conjugate CF770
Target Species Chicken, Human, Mouse, Porcine, Rat
Applications IHC-P, FC
Description Neurofilament Monoclonal Mouse Antibody (NF421)
About Neurofilament Heavy 200kDa and CF770
Neurofilament Heavy 200kDa Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]
CF770 CF®770 from Biotium is a fluorophore with an excitation peak at 770 nm and an emission peak at 797 nm. It is spectrally similar to DyeLight 800 and IRDye® 800CW.
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CF770 Excitation and Emission Spectra