Neurofilament Heavy 200kDa Monoclonal / CF488A / NF421 NFL/736

Product Details
Supplier Biotium
Catalog #: BNC880650-100 (View supplier product page)
Size 100 μl
Price $157.00
Antigen Neurofilament Heavy 200kDa
Clone NF421 NFL/736
Host Mouse
Isotype IgG
Conjugate CF488A
Target Species Chicken, Human, Mouse, Porcine, Rat
Applications IHC-P, FC
Description Neurofilament Monoclonal Mouse Antibody (NF421 + NFL/736)
About Neurofilament Heavy 200kDa and CF488A
Neurofilament Heavy 200kDa Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]
CF488A CF®488A from Biotium is a fluorophore with an excitation peak at 490 nm and an emission peak at 515 nm. It is spectrally similar to Fluorescein, Alexa Fluor™ 488 and DyLight™ 488. It can be use in fluorescence microscopy and flow cytometry. In microscopy, CF®488A has been specifically validated for STORM, STED, Structured Illumination (SIM), 2-Photon microscopy and TIRF.
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CF488A Excitation and Emission Spectra