Neurofilament Heavy 200kDa Monoclonal / CF405M / NF421 NFL/736

Product Details
Supplier Biotium
Catalog #: BNC050756-100 (View supplier product page)
Size 100 μl
Price $157.00
Antigen Neurofilament Heavy 200kDa
Clone NF421 NFL/736
Host Mouse
Isotype IgG
Conjugate CF405M
Target Species Chicken, Human, Mouse, Porcine, Rat
Applications IF, IHC-P, FC
Description Neurofilament Monoclonal Mouse Antibody (NF421 + NFL/736)
About Neurofilament Heavy 200kDa and CF405M
Neurofilament Heavy 200kDa Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]
CF405M CF®405M from Biotium is a fluorophore with an excitation peak at 408 nm and an emission peak at 452 nm. It is spectrally similar to Pacific Blue, V450 and DY-415. It can be use in fluorescence microscopy and flow cytometry. Specifically, it has been validated for use in STED, Structured Illumination (SIM) and 2-Photon microscopy. In flow cytometry, superior alternatives are Brilliant™ Violet 480, Brilliant™ Violet 510 and StarBright Violet 515.
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CF405M Excitation and Emission Spectra