CD46 Monoclonal / CF555 / 169-1-E4.3

Product Details
Supplier Biotium
Catalog #: BNC550930-500 (View supplier product page)
Size 500 μl
Price $470.00
Antigen CD46
Clone 169-1-E4.3
Host Mouse
Isotype IgG2a κ
Conjugate CF555
Target Species Baboon, Human
Applications IF, FC
Description CD46 Monoclonal Mouse Antibody (169-1-E4.3)
About CD46 and CF555
CD46 The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
CF555 CF®555 from Biotium is a fluorophore with an excitation peak at 555 nm and an emission peak at 565 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 555, ATTO 550 and DyLight™ 550. In Flow Cytometry, R-PE is a brighter alternative to CF®555. In microscopy, it has been validated for use in super-resolution imaging by STORM.
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CF555 Excitation and Emission Spectra