HDAC5 / Unconjugated / D1J7V

Citations: (32)
Product Details
Supplier Cell Signaling Technology
Catalog #: 20458S (View supplier product page)
Size 100 μl
Price $339.00
Antigen HDAC5
Clone D1J7V
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Monkey, Mouse, Rat
Applications WB, IP
Description HDAC5 (D1J7V) Rabbit mAb recognizes endogenous levels of total HDAC5 protein. This antibody does not cross-react with other HDAC proteins, including HDAC4 and HDAC7.
About HDAC5 and Purified
HDAC5 Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra