CARD11 / Unconjugated / 1D12

Citations: (24)
Product Details
Supplier Cell Signaling Technology
Catalog #: 4435S (View supplier product page)
Size 100 μl
Price $339.00
Antigen CARD11
Clone 1D12
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse
Applications WB
Description CARD11 (1D12) Rabbit mAb detects endogenous levels of total CARD11 protein.
About CARD11 and Purified
CARD11 The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra