ATP1A1 / Unconjugated /

Citations: (313)
Product Details
Supplier Cell Signaling Technology
Catalog #: 3010S (View supplier product page)
Size 100 μl
Price $306.00
Antigen ATP1A1
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Monkey, Mouse, Rat, Zebrafish
Applications WB
Description Na,K-ATPase alpha Antibody detects endogenous levels of total Na,K-ATPase alpha1 protein. Based on sequence homology, the antibody is likely to cross-react with alpha2 and alpha3 isoforms. A doublet may form if samples are boiled.
About ATP1A1 and Purified
ATP1A1 The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
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Purified Excitation and Emission Spectra