HDAC6 / PE / D2E5

Product Details
Supplier Cell Signaling Technology
Catalog #: 10421S (View supplier product page)
Size 100 μl
Price $450.00
Antigen HDAC6
Clone D2E5
Host Rabbit
Isotype IgG
Conjugate PE
Target Species Human, Monkey
Applications FC
Description HDAC6 (D2E5) Rabbit mAb (PE Conjugate) recognizes endogenous levels of total HDAC6 protein.
About HDAC6 and PE
HDAC6 Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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PE Excitation and Emission Spectra