CD45 / APC-Cy7 / HI30

Product Details
Supplier Cell Signaling Technology
Catalog #: 77322S (View supplier product page)
Size 500 μl
Price $332.00
Antigen CD45
Clone HI30
Host Mouse
Isotype IgG1
Conjugate APC-Cy7
Target Species Human
Applications FC
Description CD45 (HI30) Mouse mAb (APC-Cy7 Conjugate) recognizes endogenous levels of total CD45 protein. This antibody detects an epitope within the extracellular domain.
About CD45 and APC-Cy7
CD45 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
APC-Cy7 APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

APC-Cy7 Excitation and Emission Spectra