CD226 / Brilliant Violet 785 / 11A8

Product Details
Supplier BioLegend
Catalog #: 338321 (View supplier product page)
Size 25T
Price $198.00
Antigen CD226
Clone 11A8
Host Mouse
Isotype IgG1 κ
Conjugate Brilliant Violet 785
Target Species Human
Applications FC
Description Brilliant Violet 785 anti-human CD226 (DNAM-1)
About CD226 and Brilliant Violet 785
CD226 This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Brilliant Violet 785 Brilliant™ Violet 785 (BV785) is a far-red-emitting tandem fluorophore that can be excited by the 405 nm Violet laser and collected using a 780/60 bandpass filter. BV785 has an excitation peak at 405 nm and an emission peak at 785 nm. BV785 exhibits a medium level of brightness and is most often used in flow cytometry. Older instruments may not be set up for a dye with such a large Stokes shift, however BV785 is especially well suited for spectral cytometers or sorters. This dye is part of the Brilliant™ Violet dye line of fluorescent polymers. Brilliant™ Violet 421 polymer is employed as the donor molecule in a series of tandem dyes with acceptor molecules emitting at various points across the visible light spectrum. The Brilliant™ Violet dyes are a superior alternative to QDot nanocrystals and similar to SuperNova dye from Beckman Coulter and StarBright dyes from Bio-Rad.
Images
  CD226 Brilliant Violet 785 BioLegend antibody anti target:Human host:Mouse isotype:IgG1 κ clone:11A8

Human peripheral blood lymphocytes were stained with CD3 FITC and CD226 (clone 11A8) Brilliant Violet 785™ (left) or mouse IgG1, κ Brilliant Violet 785™ isotype control (right).

Citations
Additional
Sources
Reviews & Ratings
Brilliant Violet 785 Excitation and Emission Spectra