ABCG2 Monoclonal / Unconjugated / 5D3

Product Details
Supplier R&D Systems
Catalog #: MAB995-100 (View supplier product page)
Size 100 μg
Price $429.00
Antigen ABCG2
Clone 5D3
Host Mouse
Isotype IgG2b
Conjugate Unconjugated
Target Species Human, Mouse
Applications FC, CyTOF, WB, Block/Neutralize, ICC
Description Human ABCG2 Antibody
About ABCG2 and Purified
ABCG2 The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Purified Excitation and Emission Spectra