CD38 / DyLight 633 /

Product Details
Supplier Abbexa
Catalog #: abx200249 (View supplier product page)
Size 100 Tests
Price $420.00
Antigen CD38
Clone
Host Mouse
Isotype IgG1
Conjugate DyLight 633
Target Species Human
Applications FC
Description The monoclonal antibody is directed against the CD38-antigen, which is strongly expressed plasma cell. The CD 38-antigen is expressed at variable levels on the majority of hemopoietic cells, prevalently during early differentiation and activation.
About CD38 and DyLight 633
CD38 The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
DyLight 633 DyLight™ 633 is a red-emitting fluroescent dye that can be excited by the 628 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 633 has an excitation peak of 638 nm and an emission peak of 658 nm, and is spectrally similar to Alexa Fluor™ 633. DyLight™ 633 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 633 Excitation and Emission Spectra