FluoroFinder

	Supplier	Miltenyi Biotec
	Catalog #:	130-115-926 (View supplier product page)
	Size	30 tests in 60 µL
	Price	$160.00
	Antigen	CD180
	Clone	REA956
	Host	Human
	Isotype	IgG1
	Conjugate	PE-Vio615
	Target Species	Human
	Applications	FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
	Description	Clone REA956 recognizes the human CD180 antigen, also known as RP105, which is a 105 kDa type 1 transmembrane protein of the toll-like receptor (TLR) family. The extracellular domain of CD180 is associated with MD-1, which forms the cell surface complex RP105/MD-1. Together with TLR4, it mediates B cell recognition and signaling of LPS. RP105 is expressed on mature B cells in mantle zones as well as on monocytes, macrophages, and dendritic cells. \| Additional information: Clone REA956 displays negligible binding to Fc receptors.

	CD180	CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq, Jul 2008]
	PE-Vio615	PE-Vio®615 from Miltenyi Biotec has an excitation peak at 565 nm and an emission peak at 619 nm. It is spectrally similar to PE-eFluor™ 610, PE-Dazzle 594 and PE-CF®594

$160.00
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CD180 Monoclonal / PE-Vio615 / REA956