CD129 / DyLight 755 / RM0115-12F43

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-22493IR (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen CD129
Clone RM0115-12F43
Host Rat
Isotype IgG2
Conjugate DyLight 755
Target Species Mouse
Applications WB
Description This was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with mouse recombinant protein of the extracellular domain of IL-9 R.
About CD129 and DyLight 755
CD129 The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra