Frizzled-6 / DyLight 350 / RM0237-6H38

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-12318UV (View supplier product page)
Size 100 μl
Price $479.00
Antigen Frizzled-6
Clone RM0237-6H38
Host Rat
Isotype IgG2
Conjugate DyLight 350
Target Species Mouse
Applications WB
Description Rat Frizzled-6 antibody reacts with Mouse [DyLight 350]
About Frizzled-6 and DyLight 350
Frizzled-6 This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq, Aug 2011]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra