BMPR-IA / DyLight 488 / MM0053-8L7

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-12029G (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen BMPR-IA
Clone MM0053-8L7
Host Mouse
Isotype IgG1
Conjugate DyLight 488
Target Species Human
Applications WB, IHC-P, IHC
About BMPR-IA and DyLight 488
BMPR-IA The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra