alpha 2 Macroglobulin / DyLight 350 / MM0087-4H44

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-12032UV (View supplier product page)
Size 0.1 ml
Price $518.00
Antigen alpha 2 Macroglobulin
Clone MM0087-4H44
Host Mouse
Isotype IgG1
Conjugate DyLight 350
Target Species Human
Applications WB
About alpha 2 Macroglobulin and DyLight 350
alpha 2 Macroglobulin The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra