alpha Fetoprotein / Biotin /
alpha Fetoprotein / Biotin /
Product Details
Supplier | US Biological | |
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Catalog #: | 305687-100ug (View supplier product page) | |
Size | 100 μg | |
Price | $315.00 | |
Antigen | alpha Fetoprotein | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Biotin | |
Target Species | Mouse | |
Applications | ||
Description | Pab Rb x mouse Alpha-fetoprotein (Biotin) |
About alpha Fetoprotein and Biotin
alpha Fetoprotein | This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Oct 2019] |
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