CD268 / ATTO 488 / HuBR9.1
CD268 / ATTO 488 / HuBR9.1
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 044580-100Tests (View supplier product page) | |
| Size | 100 Tests | |
| Price | $351.75 | |
| Antigen | CD268 | |
| Clone | HuBR9.1 | |
| Host | Mouse | |
| Isotype | IgG | |
| Conjugate | ATTO 488 | |
| Target Species | Human | |
| Applications | FC | |
| Description | Mab Mo x human BAFF-R (ATTO 488) (BAFF Receptor, BR3, BlySR3, CD268, TNFRSF13C) |
About CD268 and ATTO 488
| CD268 | B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| ATTO 488 | ATTO 488 is from ATTO-Tec Gmbh has an excitation peak at 501 nm and an emission peak at 523 nm. |
Citations
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