CD11b (activation epitope) Monoclonal / PE / CBRM1/5

Product Details
Supplier EXBIO
Catalog #: 1P-172-T100 (View supplier product page)
Size 100 Tests
Price $220.00
Antigen CD11b (activation epitope)
Clone CBRM1/5
Host Mouse
Isotype IgG1 κ
Conjugate PE
Target Species Human
Applications FC, IP
Description CD11b (integrin alphaM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with integrin beta2 subunit (CD18); expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin (Mac-1, CR3) is highly expressed on NK cells, neutrophils, monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes, macrophages and granulocytes, facilitating their diapedesis, as well as it mediates the uptake of complement coated particles, serving as a receptor for the iC3b fragment of the third complement component.
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PE Excitation and Emission Spectra