CD44 / PE-Cy7 / BJ18

Citations: (5)
Product Details
Supplier BioLegend
Catalog #: 338816 (View supplier product page)
Size 100T
Price $370.00
Antigen CD44
Clone BJ18
Host Mouse
Isotype IgG1 κ
Conjugate PE-Cy7
Target Species Human
Applications FC
Description PE/Cyanine7 anti-human CD44
About CD44 and PE-Cy7
CD44 The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
PE-Cy7 PE-Cyanine®7 (PE-Cy7, RPE-Cy7) is a far red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy7. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy7, which emits light that can be captured with a 780/60 nm bandpass filter. PE-CY7 has an excitation peak at 565 nm and an emission peak at 778 nm, and is a suitable alternative to PE-Vio®770 (Miltenyi) and cFluor BYG781 (Cytek).
Images
  CD44 PE-Cy7 BioLegend antibody anti target:Human host:Mouse isotype:IgG1 κ clone:BJ18

Human peripheral blood lymphocytes were stained with CD44 (clone BJ18) PE/Cy7 (filled histogram) or mouse IgG1, κ PE/Cy7 isotype control (open histogram).
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PE-Cy7 Excitation and Emission Spectra