FluoroFinder

	Supplier	BioLegend
	Catalog #:	133613 (View supplier product page)
	Size	50 μg
	Price	$303.00
	Antigen	CD226
	Clone	TX42.1
	Host	Rat
	Isotype	IgG2a κ
	Conjugate	Brilliant Violet 605
	Target Species	Mouse
	Applications	FC
	Description	Brilliant Violet 605 anti-mouse CD226 (DNAM-1)

	CD226	This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
	Brilliant Violet 605	Brilliant™ Violet 605 (BV605) is an orange/red-emitting tandem fluorophore that can be excited by the 405 nm Violet laser and collected using a 610/20 bandpass filter. BV605 has an excitation peak at 405 nm and an and emission peak at 603 nm. BV605 is most commonly used in flow cytometry and is spectrally similar to SuperBright 600 (Thermo Fisher), SuperNova v605 (Beckman Coulter) and StarBright Violet 610 (Bio-Rad). BV605 is considered to be relatively bright and should be used on antigens of moderate to low abudance. This dye is part of the Brilliant™ Violet dye line of fluorescent polymers. Brilliant™ Violet 421 polymer is employed as the donor molecule in a series of tandem dyes with acceptor molecules emitting at various points across the visible light spectrum. The Brilliant™ Violet dyes are a superior alternative to QDot nanocrystals and similar to SuperNova dye from Beckman Coulter and StarBright dyes from Bio-Rad.

		C57BL/6 mouse splenocytes were stained with CD8 FITC and CD226 (clone TX42.1) Brilliant Violet 605™ (top) or Rat IgG2a, κ Brilliant Violet 605™ isotype control (bottom).