STAT4 (pY693) Monoclonal / APC / REA855

Citations: (3)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-114-493 (View supplier product page)
Size 100 tests in 200 µL
Price $325.00
Antigen STAT4 (pY693)
Clone REA855
Host Human
Isotype IgG1
Conjugate APC
Target Species Human
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
Description Clone REA855 recognizes the human signal transducer and activator of transcription 4 (STAT4) antigen phosphorylated at tyrosine 693 (pY693). STAT4 is a member of signal transducers and activators of the transcription (STAT) family. STAT proteins transmit signals from a receptor complex to the nucleus and activate gene expression. The seven STAT family members play a critical role in activation of signaling pathways in response to the presence of various cytokines and growth factors (interferon α (IFN-α), interferon γ (IFN-γ), EGF, PDGF, and interleukin 6 (IL-6)). STAT4 is involved in the development of Tʜ1 cells from naive CD4+ T cells and IFN-γ production in response to IL-12. | Additional information: Clone REA855 displays negligible binding to Fc receptors.
Citations
PMID 7638186
PMID 8007943
PMID 15888914
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APC Excitation and Emission Spectra