FluoroFinder

	Supplier	Miltenyi Biotec
	Catalog #:	130-114-343 (View supplier product page)
	Size	30 tests in 60 µL
	Price	$125.00
	Antigen	CXCL16
	Clone	REA873
	Host	Human
	Isotype	IgG1
	Conjugate	PE
	Target Species	Human
	Applications	FC
	Description	Clone REA873 recognizes the human CXCL16 cytokine belonging to the CXC chemokine family. It consists of a transmembrane region and a chemokine domain suspended by a mucin-like stalk. CXCL16 is secreted by dendritc cells localized in the T cell zones of lymphoid organs, and by cells found in the red pulp of the spleen. The expression of CXCL16 is induced by the inflammatory cytokines IFN-γ and TNF-α. The receptor of CXCL16 is CD186, also known as CXCR6, Bonzo, or STRL33, which is activated by CXCL16, which leads to chemotaxis of T cells. \| Additional information: Clone REA873 displays negligible binding to Fc receptors.

	CXCL16	Enables chemokine activity. Involved in several processes, including positive regulation of cell growth; response to interferon-gamma; and response to tumor necrosis factor. Located in extracellular space. Biomarker of COVID-19 and systemic scleroderma. [provided by Alliance of Genome Resources, Apr 2022]
	PE	Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.

$125.00
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CXCL16 Monoclonal / PE / REA873