CD38 / PerCP /

Product Details
Supplier Abbexa
Catalog #: abx200248 (View supplier product page)
Size 100 Tests
Price $546.00
Antigen CD38
Clone
Host Mouse
Isotype IgG1
Conjugate PerCP
Target Species Human
Applications FC
Description The monoclonal antibody is directed against the CD38-antigen, which is strongly expressed plasma cell. The CD 38-antigen is expressed at variable levels on the majority of hemopoietic cells, prevalently during early differentiation and activation.
About CD38 and PerCP
CD38 The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
PerCP Peridinin-Chlorophyll-Protein (PerCP) is a red-emitting fluorescent protein isolated from algae that can be excited by the 488 nm blue laser and captured with a 670/30 nm bandpass filter. PerCP exhibits a large Stokes' Shift, with an excitation peak at 482 nm and an emission peak at 675 nm. PerCP is was historically used in flow cytometry, however it is highly susceptible to photobleaching and has poor stability. Alternatives like BB700, NovaFluor Blue 690 or PerCP-eFluorâ„¢ 710 are preferred. PerCP is a generic dye that has no sole manufacturer.
Citations
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Reviews & Ratings
PerCP Excitation and Emission Spectra