BTK / PE / D3H5

Product Details
Supplier Cell Signaling Technology
Catalog #: 14192S (View supplier product page)
Size 100 μl
Price $450.00
Antigen BTK
Clone D3H5
Host Rabbit
Isotype IgG
Conjugate PE
Target Species Human, Mouse
Applications FC
Description Btk (D3H5) Rabbit mAb (PE Conjugate) recognizes endogenous levels of total Btk protein.
About BTK and PE
BTK The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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PE Excitation and Emission Spectra