CCR6 / PE-Dazzle 594 / 29-2L17

Citations: (7)
Product Details
Supplier BioLegend
Catalog #: 129822 (View supplier product page)
Size 100 μg
Price $405.00
Antigen CCR6
Clone 29-2L17
Host Armenian Hamster
Isotype IgG
Conjugate PE-Dazzle 594
Target Species Mouse
Applications FC
Description PE/Dazzle 594 anti-mouse CD196 (CCR6)
About CCR6 and PE-Dazzle 594
CCR6 This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
PE-Dazzle 594 PE-Dazzle® 594 (RPE-Dazzle 594) from Biolegend is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Dazzle 594. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Dazzle 594, which emitts light that can be captured with a 610/20 nm bandpass filter. PE-Dazzle 594 has an excitation peak at 565 nm and an emission peak at 610 nm, and is suitable alternative to PE-Texas Red, PE-eF610, PE-Alexa Fluor™ 610 or PE-CF®594.
Images
  CCR6 PE-Dazzle 594 BioLegend antibody anti target:Mouse host:Armenian Hamster isotype:IgG clone:29-2L17

C57BL/6 splenocytes stained with CD45R/B220 APC and CD196 (CCR6, clone 29-2L17) PE/Dazzle™ 594 (Top) or Armenian Hamster IgG isotype control PE/Dazzle™ 594 (Bottom)

  CCR6 PE-Dazzle 594 BioLegend antibody anti target:Mouse host:Armenian Hamster isotype:IgG clone:29-2L17

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PE-Dazzle 594 Excitation and Emission Spectra