CD148 / Biotin / MEM-CD148/05

Product Details
Supplier Sysmex America
Catalog #: AE191755 (View supplier product page)
Size 100 μl
Price $160.00
Antigen CD148
Clone MEM-CD148/05
Host Mouse
Isotype IgG2b
Conjugate Biotin
Target Species Human
Applications FC
Description CyFlow CD148 Biotin Conjugated Antibody
About CD148 and Biotin
CD148 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Biotin Excitation and Emission Spectra