CD326 / Alexa Fluor 488 / CO17-1A

Product Details
Supplier BioLegend
Catalog #: 369808 (View supplier product page)
Size 100T
Price $293.00
Antigen CD326
Clone CO17-1A
Host Mouse
Isotype IgG2a κ
Conjugate Alexa Fluor 488
Target Species Human
Applications FC
Description Alexa Fluor 488 anti-human CD326 (EpCAM)
About CD326 and Alexa Fluor 488
CD326 This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
Images
  CD326 Alexa Fluor 488 BioLegend antibody anti target:Human host:Mouse isotype:IgG2a κ clone:CO17-1A

Human colon carcinoma cell line HT29 was stained with CD326 (clone CO17-1A) Alexa Fluor™ 488 (filled histogram) or mouse IgG2a, κ Alexa Fluor™ 488 isotype control (open histogram).

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Alexa Fluor 488 Excitation and Emission Spectra