CD192 / Alexa Fluor 488 / K036C2

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Product Details
Supplier BioLegend
Catalog #: 357225 (View supplier product page)
Size 25T
Price $153.00
Antigen CD192
Clone K036C2
Host Mouse
Isotype IgG2a κ
Conjugate Alexa Fluor 488
Target Species Human
Applications FC
Description Alexa Fluor 488 anti-human CD192 (CCR2)
About CD192 and Alexa Fluor 488
CD192 The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
Images
  CD192 Alexa Fluor 488 BioLegend antibody anti target:Human host:Mouse isotype:IgG2a κ clone:K036C2

Human peripheral blood monocytes were stained with CD192 (clone K036C2) Alexa Fluor® 488 (filled histogram) or mouse IgG2a, κ Alexa Fluor® 488 isotype control (open histogram).

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Alexa Fluor 488 Excitation and Emission Spectra