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	Supplier	Miltenyi Biotec
	Catalog #:	130-111-124 (View supplier product page)
	Size	30 tests in 60 µL
	Price	$190.00
	Antigen	CD326
	Clone	REA764
	Host	Human
	Isotype	IgG1
	Conjugate	Vio Bright 515
	Target Species	Human
	Applications	FC, MICS (MACSima Imaging Cyclic Staining), 3D-IF, IF, IHC
	Description	Clone REA764 recognizes CD326, also known as human epithelial antigen (HEA), epithelial cell adhesion molecule (EpCAM), or epithelial-specific antigen (ESA), and is involved in cell adhesion. The CD326 antigen is broadly expressed on the basolateral surface of carcinoma and epithelial cells in tissues or on circulating tumor cells and cancer stem cells, but is not found on melanoma, neuroblastoma, sarcoma, lymphoma, leukemia cells, or normal fibroblasts. Furthermore, it is suggested, that CD326 could be used as a surface marker for human ESCs. \| Additional information: Clone REA764 displays negligible binding to Fc receptors.

	CD326	This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
	Vio Bright 515	Vio®Bright® B515 from Miltenyi has an excitation peak at 488 nm and an emission peak at 514. It is comparable to BB515 in flow cytometry.

$190.00
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CD326 Monoclonal / Vio Bright 515 / REA764