CD69 Monoclonal / Vio Blue / REA824
CD69 Monoclonal / Vio Blue / REA824
Citations:
(2)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-112-610 (View supplier product page) | |
Size | 100 tests in 200 µL | |
Price | $360.00 | |
Antigen | CD69 | |
Clone | REA824 | |
Host | Human | |
Isotype | IgG1 | |
Conjugate | Vio Blue | |
Target Species | Human | |
Applications | FC, Mass Cytometry | |
Description | Clone REA824 recognizes the human CD69 antigen, also known as activation inducer molecule (AIM). CD69 is involved in the early events of lymphocyte, monocyte, and platelet activation. Cross-linking of CD69 induces cytotoxic activity and costimulates cytokine production of activated natural killer (NK) cells and selected T cell clones. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. It is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4+ T cells in germinal centers of normal lymph nodes. | Additional information: Clone REA824 displays negligible binding to Fc receptors. |
About CD69 and Vio Blue
CD69 | This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. [provided by RefSeq, Aug 2011] | |
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Vio Blue | Vio®Blue® has an excitation peak at 400 nm and an emission peak at 455 nm, and is spectrally similar to eFluor™ 450 (ThermoFisher Scientific), V450 (BD Biosciences), Alexa Fluor™ 405 (ThermoFisher), Pacific Blue (ThermoFisher Scientific) and ATTO 425 (AttoTec). |
Citations
PMID 8340758 | ||
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PMID 8496594 | ||
Additional Sources |
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Reviews & Ratings
Vio Blue Excitation and Emission Spectra
$360.00
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