CD11b / Vio Blue / REA592
CD11b / Vio Blue / REA592
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-110-309 (View supplier product page) | |
Size | 100 Tests | |
Price | ||
Antigen | CD11b | |
Clone | REA592 | |
Host | Recombinant | |
Isotype | IgG1 | |
Conjugate | Vio Blue | |
Target Species | Human, Mouse | |
Applications | FC | |
Description | Identification and enumeration of CD11b+ cells by flow cytometry |
About CD11b and Vio Blue
CD11b | This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] | |
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Vio Blue | Vio®Blue® has an excitation peak at 400 nm and an emission peak at 455 nm, and is spectrally similar to eFluor™ 450 (ThermoFisher Scientific), V450 (BD Biosciences), Alexa Fluor™ 405 (ThermoFisher), Pacific Blue (ThermoFisher Scientific) and ATTO 425 (AttoTec). |