CD5 Monoclonal / Vio Blue / REA782
CD5 Monoclonal / Vio Blue / REA782
Citations:
(2)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-110-995 (View supplier product page) | |
Size | 100 tests in 200 µL | |
Price | $350.00 | |
Antigen | CD5 | |
Clone | REA782 | |
Host | Human | |
Isotype | IgG1 | |
Conjugate | Vio Blue | |
Target Species | Human | |
Applications | FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC, Mass Cytometry | |
Description | Clone REA782 recognizes the human CD5 antigen, a 67 kDa single-chain transmembrane glycoprotein also known as T1 or Leu-1. It is expressed on most thymocytes, the majority of peripheral T cells, a subpopulation of B cells, and B cell chronic lymphocytic leukemia (B-CLL) cells. CD5 is a receptor for the B cell antigen CD72 and plays a role in T cell activation. | Additional information: Clone REA782 displays negligible binding to Fc receptors. |
About CD5 and Vio Blue
CD5 | This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016] | |
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Vio Blue | Vio®Blue® has an excitation peak at 400 nm and an emission peak at 455 nm, and is spectrally similar to eFluor™ 450 (ThermoFisher Scientific), V450 (BD Biosciences), Alexa Fluor™ 405 (ThermoFisher), Pacific Blue (ThermoFisher Scientific) and ATTO 425 (AttoTec). |
Citations
PMID 1385158 | ||
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PMID 11861604 | ||
Additional Sources |
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Reviews & Ratings
Vio Blue Excitation and Emission Spectra
$350.00
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