CD5 Monoclonal / Vio Blue / REA782

Citations: (2)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-110-995 (View supplier product page)
Size 100 tests in 200 µL
Price $350.00
Antigen CD5
Clone REA782
Host Human
Isotype IgG1
Conjugate Vio Blue
Target Species Human
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC, Mass Cytometry
Description Clone REA782 recognizes the human CD5 antigen, a 67 kDa single-chain transmembrane glycoprotein also known as T1 or Leu-1. It is expressed on most thymocytes, the majority of peripheral T cells, a subpopulation of B cells, and B cell chronic lymphocytic leukemia (B-CLL) cells. CD5 is a receptor for the B cell antigen CD72 and plays a role in T cell activation. | Additional information: Clone REA782 displays negligible binding to Fc receptors.
About CD5 and Vio Blue
CD5 This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016]
Vio Blue Vio®Blue® has an excitation peak at 400 nm and an emission peak at 455 nm, and is spectrally similar to eFluor™ 450 (ThermoFisher Scientific), V450 (BD Biosciences), Alexa Fluor™ 405 (ThermoFisher), Pacific Blue (ThermoFisher Scientific) and ATTO 425 (AttoTec).
Citations
PMID 1385158
PMID 11861604
Additional
Sources
Reviews & Ratings
Vio Blue Excitation and Emission Spectra