CD36 Monoclonal / Vio Blue / REA760
CD36 Monoclonal / Vio Blue / REA760
Citations:
(3)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-110-882 (View supplier product page) | |
Size | 30 tests in 60 µL | |
Price | $145.00 | |
Antigen | CD36 | |
Clone | REA760 | |
Host | Human | |
Isotype | IgG1 | |
Conjugate | Vio Blue | |
Target Species | Human | |
Applications | FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC, Mass Cytometry | |
Description | Clone REA760 recognizes the human CD36 antigen, an integral membrane protein, which is a member of the class B scavenger receptor family of cell surface proteins. CD36 is expressed on various epithelial and endothelial cells as well as erythrocytes, platelets, monocytes, and macrophages, and some macrophage-derived dendritic cells. CD36 functions as a scavenger receptor for long chain fatty acids, oxidized LDL, collagen type I, IV, and V, and thrombospondin, as well as for apoptotic cells. CD36 is an early marker of erythroid differentiation. | Additional information: Clone REA760 displays negligible binding to Fc receptors. |
About CD36 and Vio Blue
CD36 | The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014] | |
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Vio Blue | Vio®Blue® has an excitation peak at 400 nm and an emission peak at 455 nm, and is spectrally similar to eFluor™ 450 (ThermoFisher Scientific), V450 (BD Biosciences), Alexa Fluor™ 405 (ThermoFisher), Pacific Blue (ThermoFisher Scientific) and ATTO 425 (AttoTec). |
Citations
PMID 2468669 | ||
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PMID 7518447 | ||
PMID 19471024 | ||
Additional Sources |
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Reviews & Ratings
Vio Blue Excitation and Emission Spectra
$145.00
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