CD73 Monoclonal / PE-Vio770 / REA804

Citations: (3)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-112-062 (View supplier product page)
Size 30 tests in 60 µL
Price $170.00
Antigen CD73
Clone REA804
Host Human
Isotype IgG1
Conjugate PE-Vio770
Target Species Human
Applications FC, MICS (MACSima Imaging Cyclic Staining), 3D-IF, IF, IHC
Description Clone REA804 recognizes the human CD73 antigen, which is a 70 kDa membrane-bound enzyme that catalyzes the conversion of AMP to bioactive adenosine at neutral pH. This glycoprotein is also called ecto-5’-nucleotidase. CD73 is present on subsets of T and B lymphocytes, follicular dendritic cells, endothelial cells, and marrow stromal cells (MSCs). | Additional information: Clone REA804 displays negligible binding to Fc receptors.
About CD73 and PE-Vio770
CD73 The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
PE-Vio770 PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.
Citations
Reviews & Ratings
PE-Vio770 Excitation and Emission Spectra