CD24 Monoclonal / PE-Vio615 / REA832

Citations: (3)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-112-853 (View supplier product page)
Size 30 tests in 60 µL
Price $165.00
Antigen CD24
Clone REA832
Host Human
Isotype IgG1
Conjugate PE-Vio615
Target Species Human
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC, Mass Cytometry
Description Clone REA832 recognizes the human CD24 antigen, which is also known as heat-stable antigen (HSA). CD24 is a glycosylphosphatidylinositol (GPI)–linked sialoglycoprotein that is anchored to the plasma membrane. CD24 has been identified to be a negative marker for breast cancer stem cells and a positive marker for ovarian or pancreatic cancer stem cells. The CD24 antibody can be used, for example, to differentiate CD44+CD24– breast cancer stem cells from CD24+ expressing cells from a primary tumor sample. Furthermore, CD24 is found on follicular dendritic cells and different epithelial and hematopoietic cell types. | Additional information: Clone REA832 displays negligible binding to Fc receptors.
About CD24 and PE-Vio615
CD24 This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells. The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. This gene was missing from previous genome assemblies, but is properly located on chromosome 6. Non-transcribed pseudogenes have been designated on chromosomes 1, 15, 20, and Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
PE-Vio615 PE-Vio®615 from Miltenyi Biotec has an excitation peak at 565 nm and an emission peak at 619 nm. It is spectrally similar to PE-eFluor™ 610, PE-Dazzle 594 and PE-CF®594
Citations
Reviews & Ratings
PE-Vio615 Excitation and Emission Spectra