CD24 Monoclonal / PE-Vio615 / REA832
CD24 Monoclonal / PE-Vio615 / REA832
Citations:
(3)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-112-853 (View supplier product page) | |
Size | 30 tests in 60 µL | |
Price | $165.00 | |
Antigen | CD24 | |
Clone | REA832 | |
Host | Human | |
Isotype | IgG1 | |
Conjugate | PE-Vio615 | |
Target Species | Human | |
Applications | FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC, Mass Cytometry | |
Description | Clone REA832 recognizes the human CD24 antigen, which is also known as heat-stable antigen (HSA). CD24 is a glycosylphosphatidylinositol (GPI)–linked sialoglycoprotein that is anchored to the plasma membrane. CD24 has been identified to be a negative marker for breast cancer stem cells and a positive marker for ovarian or pancreatic cancer stem cells. The CD24 antibody can be used, for example, to differentiate CD44+CD24– breast cancer stem cells from CD24+ expressing cells from a primary tumor sample. Furthermore, CD24 is found on follicular dendritic cells and different epithelial and hematopoietic cell types. | Additional information: Clone REA832 displays negligible binding to Fc receptors. |
About CD24 and PE-Vio615
CD24 | This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells. The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. This gene was missing from previous genome assemblies, but is properly located on chromosome 6. Non-transcribed pseudogenes have been designated on chromosomes 1, 15, 20, and Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] | |
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PE-Vio615 | PE-Vio®615 from Miltenyi Biotec has an excitation peak at 565 nm and an emission peak at 619 nm. It is spectrally similar to PE-eFluor™ 610, PE-Dazzle 594 and PE-CF®594 |
Citations
PMID 12629218 | ||
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PMID 17283135 | ||
PMID 20190812 | ||
Additional Sources |
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Reviews & Ratings
PE-Vio615 Excitation and Emission Spectra
$165.00
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