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	Supplier	Miltenyi Biotec
	Catalog #:	130-110-900 (View supplier product page)
	Size	30 tests in 60 µL
	Price	$110.00
	Antigen	CD137
	Clone	REA765
	Host	Human
	Isotype	IgG1
	Conjugate	PE
	Target Species	Human
	Applications	FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC, Mass Cytometry
	Description	Clone REA765 recognizes the human CD137 antigen, a 30 kDa glycoprotein of the tumor necrosis factor (TNF) receptor superfamily, a group of cytokines that can cause cell death (apoptosis). CD137 is mainly expressed on activated CD4+ and CD8+ T cells, activated B cells, and natural killer cells, but can also be found on resting monocytes and dendritic cells. As a costimulatory molecule it is involved in the activation and survival of CD4+ or CD8+ T cells and NK cells. CD137 has been described to be a suitable marker for antigen-specific activation of human CD8+ T cells, as it is not expressed on resting CD8+ T cells and its expression is reliably induced after 24 hours of stimulation. \| Additional information: Clone REA765 displays negligible binding to Fc receptors.

$110.00
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CD137 Monoclonal / PE / REA765